Application notes and publications

Information about known solvent mixtures that are compatible with electrospray ionisation, application notes, and examples from the literature of experiments conducted using one of our sources can be found either below or by clicking the publications link in the menu above.

Electrospray solvents & solutions

The table below contains a selection of non-volatile, fragile or complex molecules that have been successfully deposited on surfaces in high or ultra-high vacuum by electrospray and the solvent mixtures used to form the spray solutions (in all cases the simplest solvent mixture is given – other combinations may work equally well or the spray may be enhanced by the addition of other solvents). Figures in brackets indicate percentage solvents by volume.

MoleculeSolvent mixtureComments
PCBMToluene:Methanol (90:10)Dissolve first in toluene then add methanol
P3HTToluene:Methanol (90:10)Dissolve first in toluene then add methanol and filter
PCBM:P3HT MixtureToluene:Methanol (90:10)Dissolve individually first in toluene then add methanol, then mix the two solutions in desired ratio
C60Toluene:Methanol (90:10)Dissolve first in toluene then add methanol
Ru535 Dye (aka N3)Methanol (100)
Ru470 DyeMethanol (100)
PEDOT:PSS Water:Methanol (50:50)Dissolve first in water then add methanol
Fibronectin proteinPhosphate Saline Buffer:Methanol (50:50)Supplied in buffer solution to which methanol is added
Fluorescein Methanol (100)
Gold nanoparticles Citrate Buffer:Water (20:80)
PLGA Acetone (100)No issues
PEG:PEO Methanol (100)
PVP Methanol (100)
Rhodamine 6G Methanol (100)
SQ2 Dye Methanol (100)
Mn12(acetate)16 Single molecule magnetsMethanol (100)
Mn12(benzoate)16 Single molecule magnetsMethanol (100)